An Essential Warning

An early warning on early warning systems!

Bureaucratic Justice : an Early Warning *

To accommodate the staggering increase in federal litigation that has occurred in recent years, the federal judicial process has been gradually, but significantly, transformed. The number of federal judges has dramatically increased at both the trial and appellate levels.' The number of law clerks and "staff attorneys" employed in the courts of appeals also has grown dramatically.2 Moreover, an...

Brugada Syndrome: An Electrical Storm without Warning.

Brugada Syndrome (BrS) is an inherited channelopathy causing sodium channel dysfunction in cardiac myocyte. These patients are prone to develop Ventricular Fibrillation (VF) or polymorphic Ventricular Tachycardia (VT). Next to coronary artery disease and cardiomyopathies, BrS is an important cause of sudden cardiac death. We report here a case of 22 year unmarried female with "unexplained" card...

An early warning system for DNA damage

A close look at cerebellar learning he cerebellum handles many motor coordination and reflexive behaviors, and learned adaptations of these behaviors are thought to require synaptic long-term depression (LTD). On page 295, Feil et al. identify a signaling pathway essential for LTD in cerebellar Purkinje cells but, surprisingly, this pathway is required only for a subset of motor reflex adaptati...

An early warning method for crush

Fatal crush conditions occur in crowds with tragic frequency. Event organizers and architects are often criticised for failing to consider the causes and implications of crush, but the reality is that the prediction and mitigation of such conditions offers a significant technical challenge. Full treatment of physical force within crowd simulations is precise but computationally expensive; the m...